Genetic factors in intervertebral disc degeneration
نویسندگان
چکیده
منابع مشابه
Intervertebral disc degeneration: biological and biomechanical factors
cluding cytokines, growth factors, enzymes, and enzyme inhibitors, in a paracrine or/and autocrine fashion.1,2 Anabolic regulators include polypeptide growth factors, such as insulin-like growth factor (IGF), transforming growth factor-β (TGF-β), and the bone morphogenetic proteins (BMPs).1–4 Other small molecules, such as the synthetic peptide of link protein, have also been reported to be reg...
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Intervertebral disc degeneration remains a pervasive and intractable disease arising from a combination of aging and stress on the back and spine. The growing field of regenerative medicine brings the promise of stem cells in the treatment of disc disease. Scientists and physicians hope to employ stem cells not only to stop, but also reverse degeneration. However, there are many important outst...
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ژورنال
عنوان ژورنال: Genes & Diseases
سال: 2016
ISSN: 2352-3042
DOI: 10.1016/j.gendis.2016.04.005